COVID-19 SERVICE UPDATE – JANUARY 2021

HAPPY NEW YEAR AND ALL THE BEST IN 2021


Shipping Update

We are now seeing improvements in our shipping times. However, things are not yet back to normal and there are still some delays occurring.

Our normal shipping time averages 1 - 2 weeks. Shipments may potentially take an additional 2 – 4 weeks to arrive, depending on the source country of your order. Shipments from the United Kingdom and Canada are generally quicker than from other countries.

Please note that these times are averages and individual shipping times will vary. We highly recommend that you place your order at least 2 – 4 weeks or more ahead of your normal reorder time to avoid running out of your medication.

These delays are temporary, and we thank the shipping and delivery personnel who are working hard for all of us during this global crisis.

Please Note: We have resumed our normal 30-Day Shipping Guarantee. We will provide updates as the situation changes.

Call Center

Our call center hours of operation are 6:00 am – 9:00 pm Central Time on Monday to Friday, and 7:00 am – 7:00 pm Central Time on Saturday and Sunday.

If you are experiencing increased hold times or are calling outside of these hours, please leave us a message or send us an email and we will get back to you as soon as we can. Due to increased demand on telephone networks worldwide, you may experience some intermittent connection problems. If this happens our agents will call you back.

Our Commitment

If you have any questions about any changes in our service please do not hesitate to contact us. Our staff are working tirelessly to ensure the timely fulfillment and delivery of all orders. The health and safety of our customers and staff is our highest priority and we remain committed to providing service at the highest level.

We appreciate your business and thank you for your continued support.


Management and Staff
Medix Pharmacy

Aptiom
(Eslicarbazepine Acetate)

Prescription Settings Edit

Brand Name Choices

Aptiom 200mg
Aptiom 200mg

Eslicarbazepine Acetate

Manufactured by Sunovion Pharmaceuticals

Product of Canada

Dispensed by an approved Canadian pharmacy partner

Prescription Required

Aptiom 400mg
Aptiom 400mg

Eslicarbazepine Acetate

Manufactured by Sunovion Pharmaceuticals

Product of Canada

Dispensed by an approved Canadian pharmacy partner

Prescription Required

Aptiom 600mg
Aptiom 600mg

Eslicarbazepine Acetate

Manufactured by Sunovion Pharmaceuticals

Product of Canada

Dispensed by an approved Canadian pharmacy partner

Prescription Required

Aptiom 800mg
Aptiom 800mg

Eslicarbazepine Acetate

Manufactured by Sunovion Pharmaceuticals

Product of Canada

Dispensed by an approved Canadian pharmacy partner

Prescription Required

Aptiom 800mg
Aptiom 800mg

Marketed as Zebinix in United Kingdom

Eslicarbazepine Acetate

Manufactured by Eisai

Product of United Kingdom

Dispensed by a licensed pharmacy in the United Kingdom

Prescription Required

Parallel Import

More Brand Name Choices

Generic Choices

No generic medication is available for Aptiom (Eslicarbazepine Acetate)

What Aptiom is and what it is used for

Zebinix contains the active substance eslicarbazepine acetate. Zebinix belongs to a group of medicines called antiepileptics used to treat epilepsy, a condition where someone has repeated seizures or fits. Zebinix is used:
• on its own (monotherapy) in adult patients with newly diagnosed epilepsy
• with other antiepileptic medicines (adjunctive therapy), in adult, adolescents and children patients above 6 years of age who are experiencing seizures that affect one part of the brain (partial seizure). These seizures may or may not be followed by a seizure affecting all of the brain (secondary generalisation) Zebinix has been given to you by your doctor to reduce your number of seizures.

How to take Aptiom

Always take this medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure. Adults Dose when you start treatment 400 mg once daily for one or two weeks, before increasing to the maintenance dose. Your doctor will decide whether you will be given this dose for one or two weeks. Maintenance dose The usual maintenance dose is 800 mg once daily. Depending on how you respond to Zebinix, your dose may be increased to 1,200 mg once daily. If you are taking Zebinix on its own your doctor may consider you can benefit of a dose of 1,600 mg once daily. Patients with kidney problems If you have kidney problems you will usually be given a lower dose of Zebinix. Your doctor will work out the correct dose for you. Zebinix is not recommended if you have severe kidney problems. Elderly (over 65 years of age) If you are elderly and taking Zebinix on its own the dose of 1,600 mg is not a suitable dose for you. Children above 6 years of age Dose when you start treatment The starting dose is 10 mg per kg body weight taken once a day for one or two weeks, before increasing to the maintenance dose. Maintenance dose Depending on the response to Zebinix, the dose may be increased by 10 mg per kg body weight, at intervals of one or two weeks, up to 30 mg per kg body weight. The maximum dose is 1,200 mg once daily. Children with ≥60 kg Children with 60 kg or more body weight should take the same dose as adults. Other form of this medicine, like oral suspension, maybe more suitable for children. Ask your doctor or pharmacist. Method and route of administration Zebinix is for oral use. Swallow the tablet with a glass of water. Zebinix tablets may be taken with or without food. If you take more Zebinix than you should If you accidently take more Zebinix than you should, you may feel or walk unsteady or have muscular weakness on one side of the body. Tell a doctor or go to a hospital accident and emergency department immediately. Take the medicine pack with you. This is so the doctor knows what you have taken. If you forget to take Zebinix If you forget to take a tablet, take it as soon as you remember and carry on as usual. Do not take a double dose to make up for a forgotten dose. If you stop taking Zebinix Do not stop taking your tablets suddenly. If you do, you are at risk of having more seizures. Your doctor will decide how long you should take Zebinix. Should your doctor decide to stop your treatment with Zebinix your dose will usually be reduced gradually. It is important that your treatment is completed as advised by your doctor or your symptoms may get worse. If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

The following side effects can be very serious. If they happen to you stop taking Zebinix and tell a doctor or go to a hospital immediately, as you may need urgent medical treatment:
• blistering or peeling of the skin and/or mucous membranes, rash, swallowing or breathing problems, swelling of your lips, face, eyelids, throat or tongue. These could be signs of an allergic reaction.

Very common (may affect more than 1 in 10 people) side effects are:
• Feeling dizzy or sleepy.

Common (may affect up to 1 in 10 people) side effects are:
• Feeling unsteady or having a sensation of spinning or floating;
• Feeling sick or vomiting;
• Headache;
• Diarrhoea;
• Seeing double or blurred vision;
• Difficulty in concentration;
• Feeling low in energy or tired;
• Shaking;
• Skin rash;
• Blood tests showing that you have low levels of sodium in your blood;
• Decrease of appetite;
• Difficulty in sleeping;
• Difficulty in coordinating movements (ataxia).

Uncommon (may affect up to 1 in 100 people) side effects are:
• Clumsiness;
• Allergy;
• Constipation;
• Seizures;
• Underactive thyroid gland. Symptoms include decreased level of thyroid hormone levels (seen in blood tests), cold intolerance, large tongue, thin and brittle fingernails or hair and low body temperature;
• Liver problems;
• High blood pressure or severe increase in blood pressure;
• Low blood pressure or a fall in blood pressure on standing up;
• Blood tests showing that you have low levels of salts (including chloride) in your blood or a reduction in red blood cells;
• Dehydration;
• Eye movement changes, fuzzy vision or red eye;
• Having falls;
• Thermal burn;
• Poor memory or forgetfulness;
• Crying, feeling depressed, nervous or confused, lack of interest or emotion;
• Inability to speak or write or understand spoken or written language;
• Agitation;
• Attention deficit/ hyperactivity disorder;
• Irritability;
• Mood changes or hallucinations;
• Difficulty in speaking;
• Nosebleed;
• Chest pain;
• Tingling and/or feeling numb in any part of your body;
• Migraine;
• Burning sensation;
• Abnormal sense of touch;
• Disturbances in the sense of smell;
• Ringing in the ears;
• Hearing difficulty;
• Swelling in your legs and arms;
• Heart burn, stomach upset, abdominal pain, abdominal bloating and discomfort or dry mouth;
• Charcoal (dark) stool;
• Inflamed gums or toothache;
• Sweating or having dry skin;
• Itching;
• Skin changes (e.g. red skin);
• Hair loss;
• Urinary tract infection;
• Feeling generally weak, unwell or having chills;
• Weight loss;
• Muscle pain, pain in limbs, muscular weakness;
• Bone metabolism disorder;
• Increased bone proteins;
• Flushing, cold limbs;
• Slower or irregular heart beat;
• Feeling extremely sleepy;
• Sedation;
• Neurological movement disorder where your muscles contract causing twisting and repetitive movements or abnormal postures. Symptoms include tremors, pain, cramping;
• Medicine toxicity;
• Anxiety.

Not known (frequency cannot be estimated from available data) side effects are:
• Reduction in blood platelets which increases risk of bleeding or bruising;
• Severe pain in the back and stomach (caused by inflamation of the pancreas);
• Reduction in white blood cells which makes infections more likely;
• Reddish target-like macules or circular patches often with central blisters on the trunk, skin peeling, ulcers of mouth, throat, nose, genitals and eyes, red and swollen eyes and can be preceded by fever and/or flu-like symptoms (Stevens-Johnson syndrome/toxic epidermal necrolysis);
• Initially flu-like symptoms, rash on the face then widespread rash, high body temperature, liver enzyme elevations, blood abnormalities (eosinophilia), enlarged lymph nodes and other body organs involvement (Drug Reaction with Eosinophilia and Systemic Symptoms which is also known as DRESS or drug hypersensitivity syndrome);
• Serious allergic reaction which causes swelling of the face, throat, hand, feet, ankles, or lower legs;
• Urticaria (skin rash with itching).
• The use of Zebinix is associated with an abnormality in ECG (electrocardiogram) called increase in PR interval. Side effects associated with this ECG abnormality (e.g. fainting and slowing of heart beat) may occur. There have been reports of bone disorders including osteopenia and osteoporosis (thinning of the bone) and fractures with structurally related antiepileptics medicines like carbamazepine and oxcarbazepine. Check with your doctor or pharmacist, if you are on long-term antiepileptic treatment, have a history of osteoporosis, or take steroids.

Reporting of side effects If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme: www.mhra.gov.uk/yellowcard By reporting side effects you can help provide more information on the safety of this medicine.

How to Store Aptiom

Keep this medicine out of the sight and reach of children. Do not use this medicine after the expiry date, which is stated on the blister, bottle and the carton after EXP. The expiry date refers to the last day of that month. This medicine does not require any special storage conditions. Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.

Fast Shipping

2 to 3 weeks on average

The average shipping time is 2 weeks in North America and 4 weeks internationally. We offer free shipping on all orders shipped to North America. Shipping is a flat rate of $20.00 for all other countries.

Price Match Guarantee

If you have been prescribed medication by your doctor and cannot afford the high price at your local pharmacy, Medix Pharmacy is the solution for you. All orders are backed with a price match and satisfaction guarantee.

Your Trusted Pharmacy Referral Service

Medix Pharmacy is an international pharmacy referral service. With a network of licensed pharmacy partners in Canada, United Kingdom, Australia, and New Zealand, we are able to help you lower the costs of your medications.

Our pharmacy partners are all thoroughly vetted and qualified to ensure that the medication you receive is cost effective, safe and effective. Because we only work with licensed pharmacies, you can rest assured that your medication is safe, effective, and genuine.

  • Free standard delivery to your door, to any international address
  • Option to add Tracked Deliveries
  • Handy reminders to re-order so you do not run out
  • Professional & Knowledgeable Customer Services Team
  • Save time, with no need for repeated trips to your physician or local drugstore

With a dedicated customer service team, free standard shipping, and a record of providing significant saving for our customers, we believe that you do not need to compromise quality or safety in your search for value.

If you are unable to find your prescribed medicine on our website, please fill out the form below and we will confirm pricing and availability within 1 business day. You may also call us at 1-866-500-6633 and one of our patient care representatives will be happy to assist you.