Shipping Update - May 1 2022

Shipping times are now closer to normal. However, due to the latest outbreak of the highly contagious Omicron strain, some delays in shipping times may still occasionally occur. We will provide updates as the situation changes.

Our normal shipping time averages 1 - 2 weeks. Shipments may sometimes take an additional 2 weeks to arrive, depending on the source country of your order.

Please note that these times are averages and individual shipping times will vary. We recommend that you place your order at least 2 - 4 weeks or more ahead of your normal reorder time to avoid running out of your medication.

We offer a shipping guarantee when you place an order with us. If your order does not arrive within 6 weeks from the date it was shipped, we will re-ship your order to you at no additional cost.

Call Center - New Hours effective April 1, 2022

Our call center hours of operation are now 6:00 am - 9:00 pm Central Time on Monday to Friday, and 7:00 am - 7:00 pm Central Time on Saturday and Sunday.

If you are experiencing increased hold times or are calling outside of these hours, please leave us a message or send us an email and we will get back to you as soon as we can. Due to increased demand on telephone networks worldwide, you may experience some intermittent connection problems. If this happens our agents will call you back.

Our Commitment

If you have any questions about any changes in our service please do not hesitate to contact us. Our staff are working tirelessly to ensure the timely fulfillment and delivery of all orders. The health and safety of our customers and staff is our highest priority and we remain committed to providing service at the highest level.

We appreciate your business and thank you for your continued support.

Management and Staff
Medix Pharmacy

(Diclofenac Sodium/Misoprostol)

Prescription Settings Edit

Brand Name Choices

Arthrotec 50mg/200mcg
Arthrotec 50mg/200mcg Delayed Release Tablets

Marketed as Arthrotec 50 in United Kingdom

Diclofenac Sodium/Misoprostol

Manufactured by Pfizer Ltd

Product of United Kingdom

Dispensed by a licensed pharmacy in the United Kingdom

Prescription Required

Parallel Import

Arthrotec 75mg/200mcg
Arthrotec 75mg/200mcg Delayed Release Tablets

Marketed as Arthrotec 75 in United Kingdom

Diclofenac Sodium/Misoprostol

Manufactured by Pfizer

Product of United Kingdom

Dispensed by a licensed pharmacy in the United Kingdom

Prescription Required

Parallel Import

Generic Choices

Diclofenac Sodium/Misoprostol 75mg/200mcg
Diclofenac Sodium/Misoprostol 75mg/200mcg Delayed Release Tablets

Generic Equivalent of Arthrotec 75mg/200mcg

Manufactured by Various UK Generic Manufacturers (MHRA Approved)

Product of United Kingdom

Dispensed by a licensed pharmacy in the United Kingdom

Prescription Required

What Arthrotec is and what it is used for

Arthrotec helps to relieve the pain and swelling of rheumatoid arthritis and osteoarthritis, and may help to protect patients at risk of irritation or ulceration of the stomach or intestines. Arthrotec contains diclofenac and misoprostol. Diclofenac belongs to a group of medicinal products called Non-Steroidal Anti-Inflammatory drugs (NSAIDs). Although NSAIDs relieve the pain, they can reduce the amount of natural protective substances called prostaglandins in the stomach lining. This means that NSAIDs can lead to stomach upsets or stomach ulcers. Arthrotec also contains misoprostol which is very similar to these prostaglandins and may help protect your stomach.

How to take Arthrotec

Always take this medicine exactly as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure. The recommended dose is one tablet two or three times a day, or as directed by your doctor. Arthrotec should be swallowed whole with a drink of water (not chewed), taken during or after mealtimes. In the elderly and patients with liver or kidney disorders, your doctor may want to monitor you more closely. No change in dose is needed. Use in children: Arthrotec is for adults only, it is not for use in children (under 18 years). If you take more Arthrotec than you should You should not take more tablets than your doctor tells you to. If you take too many tablets contact your doctor, pharmacist or hospital as soon as possible, and take your medicine with you. If you forget to take Arthrotec If you forget to take a tablet, take it as soon as you remember. Do not take a double dose to make up for a forgotten dose. If you stop taking Arthrotec Do not stop taking Arthrotec unless your doctor tells you to. If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them. If you are worried about side effects, ask your doctor. It is important that you know what can happen, so that you can take action if Arthrotec does have a side effect. Arthrotec sometimes causes side effects but these usually go away during treatment as your body gets used to the medicine. If any of the following happen, stop taking Arthrotec and tell your doctor immediately: If you have
• Weakness of or inability to move one side of body, slurred speech (stroke) or chest pain (heart attack) – the occurrence is uncommon
• Shortness of breath – the occurrence is uncommon
• Severe stomach pain or any sign of bleeding or rupture in the stomach or intestines, such as passing black or bloodstained stools, or vomiting blood – this occurs very rarely
• A serious skin reaction such as rash, blistering or peeling of the skin (Stevens-Johnson syndrome, exfoliative dermatitis and toxic epidermal necrolysis) – this occurs very rarely
• Heart failure, chest pain, palpitations (awareness of your heartbeat) – this occurs very rarely
• A serious allergic reaction such as skin rash, swelling of the face, wheezing or difficulty breathing (anaphylactic shock) – this occurs rarely
• Jaundice (your skin or the whites of your eyes look yellow) – this occurs rarely
• Arthrotec can cause a decrease in a type of white blood cell (these help protect the body from infection and disease) and lead to infections with symptoms like chills, sudden fever, sore throat, or flu-like symptoms. Immediately contact your doctor if any of these symptoms develop – it is not known how often this occurs
• Reduction in the number of blood platelets (increased chance of bleeding or bruising) – it is not known how often this occurs
• If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet.

Very common: may affect more than 1 in 10 people
• Stomach ache, diarrhoea, nausea (feeling sick), indigestion Diarrhoea is the most common problem and is occasionally severe. You have less chance of getting diarrhoea if you take Arthrotec with food. If you use an antacid (something to reduce acid in the stomach) you should avoid antacids with magnesium in them as these may make diarrhoea worse. Your pharmacist can help you choose a suitable antacid. If this diarrhoea continues and is severe tell your doctor.

Common: may affect up to 1 in 10 people
• Rash, itching
• Vomiting, wind, constipation, burping, gastritis (indigestion, stomach ache, vomiting)
• Ulcers in the stomach or intestines
• Headache, dizziness
• Difficulty sleeping
• Changes in blood tests relating to the liver
• Inflammation of the digestive tract, including the intestines, such as nausea, diarrhoea, abdominal pain
• Abnormal formation of foetus

Uncommon: may affect up to 1 in 100 people
• Swelling of the mouth
• Abnormal or unexpected bleeding from the vagina, menstrual disturbances
• Reduction in the number of blood platelets (increased chance of bleeding or bruising)
• Purpura (purple spots on the skin)
• Urticaria (raised itchy rash)
• Infection of the vagina (itching, burning, soreness, pain especially during intercourse and/or urination)
• Blurred vision
• High blood pressure
• Menstrual disorders such as usually heavy or light bleeding, or delayed periods
• Chills or fever

Rare: may affect up to 1 in 1,000 people
• Inflammation of the liver (possible yellow discoloration of skin, headache, fever, chills, general weakness)
• Inflammation of the pancreas, which causes severe pain in the abdomen and back
• Inflammation of the lung such as coughing, increased sputum
• Breast pain

Very rare: may affect up to 1 in 10,000 people
• Severe liver disorders including liver failure
• Nightmares

Not known: frequency cannot be estimated from the available data
• Damage to the gullet
• Worsening of ulcerative colitis or Crohn’s disease (inflammation of the intestines)
• Kidney or liver problems
• Seizures
• Allergic reaction, including asthma, breathing problems, itching, hair loss, inflamed blood vessels (can cause fever, aches, purple blotches)
• Symptoms of meningitis (stiff neck, headache, nausea (feeling sick), vomiting, fever or loss of consciousness)
• Fluid build-up in the body that can cause swollen ankles and legs
• Vomiting blood
• Psychotic reactions (mental disorder that features loss of contact with reality)
• Swelling of the tongue, mouth ulcers, dry mouth
• Depression, feeling anxious, mood swings, irritability, memory problems, feeling confused, feeling shaky, drowsiness, tiredness
• Difficulty seeing, ringing in the ears, changes in the way things taste
• Increased sensitivity to light
• Inflammation
• Loss of appetite
• Abnormal contractions of the womb, rupture in the womb, retained placenta after giving birth, a life-threatening reaction in the mother due to the passage of amniotic fluid (fluid covering the fetus) or other foetal material into the maternal blood stream, bleeding in the womb, miscarriage, death of the unborn baby, premature birth
• Low blood pressure
• Anaemia (low number of red blood cells) which can lead to pale skin and cause weakness or breathlessness
• Painful menstrual/period cramps
• Decreased fertility in females

Reporting of side effects If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at: or search for MHRA Yellow Card in the Google Play or Apple App Store. By reporting side effects you can help provide more information on the safety of this medicine.

How to Store Arthrotec

Keep this medicine out of the sight and reach of children. Do not store above 25°C. Store in the original packaging. Do not use this medicine after the expiry date which is stated on the blister and carton. The expiry date refers to the last day of that month. Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.

Fast Shipping

Fast Shippings

2 to 3 weeks on average

The average shipping time is 2 weeks in North America and 4 weeks internationally. We offer free shipping on all orders shipped to North America. Shipping is a flat rate of $20.00 for all other countries.

Price Match Guarantee

Price Match Guarantees

If you have been prescribed medication by your doctor and cannot afford the high price at your local pharmacy, Medix Pharmacy is the solution for you. All orders are backed with a price match and satisfaction guarantee.

Your Trusted Pharmacy Referral Service

Medix Pharmacy is an international pharmacy referral service. With a network of licensed pharmacy partners in Canada, United Kingdom, Australia, and New Zealand, we are able to help you lower the costs of your medications.

Our pharmacy partners are all thoroughly vetted and qualified to ensure that the medication you receive is cost effective, safe and effective. Because we only work with licensed pharmacies, you can rest assured that your medication is safe, effective, and genuine.

  • Free standard delivery to your door, to any international address
  • Option to add Tracked Deliveries
  • Handy reminders to re-order so you do not run out
  • Professional & Knowledgeable Customer Services Team
  • Save time, with no need for repeated trips to your physician or local drugstore

With a dedicated customer service team, free standard shipping, and a record of providing significant saving for our customers, we believe that you do not need to compromise quality or safety in your search for value.

If you are unable to find your prescribed medicine on our website, please fill out the form below and we will confirm pricing and availability within 1 business day. You may also call us at 1-866-500-6633 and one of our patient care representatives will be happy to assist you.