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What Augmentin is and what it is used for
Augmentin is an antibiotic and works by killing bacteria that cause infections. It contains two different
medicines called amoxicillin and clavulanic acid. Amoxicillin belongs to a group of medicines called
“penicillins” that can sometimes be stopped from working (made inactive). The other active component
(clavulanic acid) stops this from happening.
Augmentin is used in babies and children to treat the following infections:
• middle ear and sinus infections
• respiratory tract infections
• urinary tract infections
• skin and soft tissue infections including dental infections
• bone and joint infections.
How to take Augmentin
Always give this medicine exactly as your doctor or pharmacist has told you. Check with your doctor or
pharmacist if you are not sure.
Adults and children weighing 40 kg or over
• This suspension is not usually recommended for adults and children weighing 40 kg and over. Ask your doctor or pharmacist for advice. Children weighing less than 40 kg All doses are worked out depending on the child’s bodyweight in kilograms.
• Your doctor will advise you how much Augmentin you should give to your baby or child.
• You may be provided with a plastic measuring spoon or plastic measuring cup or dosing syringe. You should use this to give the correct dose to your baby or child.Recommended dose
•20 mg/5 mg to 60 mg/15 mg for each kilogram of body weight a day, given in three divided doses. Patients with kidney and liver problems
• If your child has kidney problems the dose might be lowered. A different strength or a different medicine may be chosen by your doctor.
• If your child has liver problems they may have more frequent blood tests to see how their liver is working. How to give Augmentin
• Always shake the bottle well before each dose
• Give with a meal
• Space the doses evenly during the day, at least 4 hours apart. Do not take 2 doses in 1 hour.
• Do not give your child Augmentin for more than 2 weeks. If your child still feels unwell they should go back to see the doctor. If you give more Augmentin than you should If you give your child too much Augmentin, signs might include an upset stomach (feeling sick, being sick or diarrhoea) or convulsions. Talk to their doctor as soon as possible. Take the medicine bottle to show the doctor. If you forget to give Augmentin If you forget to give your child a dose, give it as soon as you remember. You should not give your child the next dose too soon, but wait about 4 hours before giving the next dose. Do not take a double dose to make up for a forgotten dose. If your child stops taking Augmentin Keep giving your child Augmentin until the treatment is finished, even if they feel better. Your child needs every dose to help fight the infection. If some bacteria survive they can cause the infection to come back. If you have any further questions on the use of this medicine, ask your doctor, pharmacist or nurse.
Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them. The side
effects below may happen with this medicine.
Conditions you need to look out for
• skin rash
• inflammation of blood vessels (vasculitis) which may be visible as red or purple raised spots on the skin, but can affect other parts of the body
• fever, joint pain, swollen glands in the neck, armpit or groin
• swelling, sometimes of the face or throat (angioedema), causing difficulty in breathing
• collapse. Contact a doctor immediately if your child gets any of these symptoms. Stop taking Augmentin. Inflammation of large intestine Inflammation of the large intestine, causing watery diarrhoea usually with blood and mucus, stomach pain and/or fever. Contact your doctor as soon as possible for advice if your child gets these symptoms.
Very common side effects These may affect more than 1 in 10 people
• diarrhoea (in adults).
Common side effects
• These may affect up to 1 in 10 people thrush (candida
•a yeast infection of the vagina, mouth or skin folds)
• feeling sick (nausea), especially when taking high doses if affected take Augmentin with a meal
• diarrhoea (in children).
Uncommon side effects These may affect up to 1 in 100 people
• skin rash, itching
• raised itchy rash (hives)
Uncommon side effects that may show up in blood tests:
• increase in some substances (enzymes) produced by the liver.
Rare side effects These may affect up to 1 in 1000 people
• skin rash, which may blister, and looks like small targets (central dark spots surrounded by a paler area, with a dark ring around the edge
•erythema multiforme) if you notice any of these symptoms contact a doctor urgently.
Rare side effects that may show up in blood tests:
• low number of cells involved in blood clotting
• low number of white blood cells. Frequency not known Frequency cannot be estimated from available data.
• Allergic reactions (see above)
• Inflammation of the large intestine (see above)
• Inflammation of the protective membrane surrounding the brain (aseptic meningitis)
• Serious skin reactions:
•a widespread rash with blisters and peeling skin, particularly around the mouth, nose, eyes and genitals (Stevens-Johnson syndrome), and a more severe form, causing extensive peeling of the skin (more than 30% of the body surface
•toxic epidermal necrolysis)
•widespread red skin rash with small pus-containing blisters (bullous exfoliative dermatitis)
•a red, scaly rash with bumps under the skin and blisters (exanthemous pustulosis).
•flu-like symptoms with a rash, fever, swollen glands, and abnormal blood test results (including increased white blood cells (eosinophilia) and liver enzymes) (Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)). Contact a doctor immediately if your child gets any of these symptoms.
• inflammation of the liver (hepatitis)
• jaundice, caused by increases in the blood of bilirubin (a substance produced in the liver) which may make your child’s skin and whites of the eyes appear yellow
• inflammation of tubes in the kidney
• blood takes longer to clot
• convulsions (in people taking high doses of Augmentin or who have kidney problems)
• black tongue which looks hairy
• stained teeth (in children), usually removed by brushing. Side effects that may show up in blood or urine tests:
• severe reduction in the number of white blood cells
• low number of red blood cells (haemolytic anaemia)
• crystals in urine.
Reporting of side effects If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard or by searching for MHRA Yellow Card in the Google Play or Apple App Store. By reporting side effects you can help provide more information on the safety of this medicine.
How to Store Augmentin
Keep this medicine out of the sight and reach of children.
Store in the original package in order to protect from moisture.
Do not store above 25°C.
Do not use this medicine after the expiry date (EXP) which is stated on the carton. The expiry date refers
to the last day of that month.
Store in a refrigerator (2°C
•8°C). Do not freeze. Once made up, the suspension should be used within 7 days. Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help you to protect the environment.
2 to 3 weeks on average
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