COVID-19 SERVICE UPDATE – JANUARY 2021

HAPPY NEW YEAR AND ALL THE BEST IN 2021


Shipping Update

We are now seeing improvements in our shipping times. However, things are not yet back to normal and there are still some delays occurring.

Our normal shipping time averages 1 - 2 weeks. Shipments may potentially take an additional 2 – 4 weeks to arrive, depending on the source country of your order. Shipments from the United Kingdom and Canada are generally quicker than from other countries.

Please note that these times are averages and individual shipping times will vary. We highly recommend that you place your order at least 2 – 4 weeks or more ahead of your normal reorder time to avoid running out of your medication.

These delays are temporary, and we thank the shipping and delivery personnel who are working hard for all of us during this global crisis.

Please Note: We have resumed our normal 30-Day Shipping Guarantee. We will provide updates as the situation changes.

Call Center

Our call center hours of operation are 6:00 am – 9:00 pm Central Time on Monday to Friday, and 7:00 am – 7:00 pm Central Time on Saturday and Sunday.

If you are experiencing increased hold times or are calling outside of these hours, please leave us a message or send us an email and we will get back to you as soon as we can. Due to increased demand on telephone networks worldwide, you may experience some intermittent connection problems. If this happens our agents will call you back.

Our Commitment

If you have any questions about any changes in our service please do not hesitate to contact us. Our staff are working tirelessly to ensure the timely fulfillment and delivery of all orders. The health and safety of our customers and staff is our highest priority and we remain committed to providing service at the highest level.

We appreciate your business and thank you for your continued support.


Management and Staff
Medix Pharmacy

Avapro
(Irbesartan)

Prescription Settings Edit

Brand Name Choices

Avapro 75mg
Avapro 75mg

Irbesartan

Manufactured by Sanofi Aventis Canada Inc

Product of Canada

Dispensed by an approved Canadian pharmacy partner

Prescription Required

Avapro 150mg
Avapro 150mg

Marketed as Aprovel in United Kingdom

Irbesartan

Manufactured by Sanofi Aventis

Product of United Kingdom

Dispensed by a licensed pharmacy in the United Kingdom

Prescription Required

Parallel Import

Avapro 150mg
Avapro 150mg

Irbesartan

Manufactured by Sanofi Aventis Canada Inc

Product of Canada

Dispensed by an approved Canadian pharmacy partner

Prescription Required

Avapro 300mg
Avapro 300mg

Irbesartan

Manufactured by Sanofi Aventis Canada Inc

Product of Canada

Dispensed by an approved Canadian pharmacy partner

Prescription Required

Avapro 300mg
Avapro 300mg

Irbesartan

Manufactured by Sanofi Aventis

Product of Australia

Dispensed by an international pharmacy partner

Prescription Required

More Brand Name Choices

Generic Choices

Irbesartan 75mg
Irbesartan 75mg

Generic Equivalent of Avapro 75mg

Manufactured by Various UK Generic Manufacturers (MHRA Approved)

Product of United Kingdom

Dispensed by a licensed pharmacy in the United Kingdom

Prescription Required

Irbesartan 150mg
Irbesartan 150mg

Marketed as Sandoz-Irbesartan in Canada

Generic Equivalent of Avapro 150mg

Manufactured by Sandoz

Product of Canada

Dispensed by an approved Canadian pharmacy partner

Prescription Required

Irbesartan 150mg
Irbesartan 150mg

Generic Equivalent of Avapro 150mg

Manufactured by Various UK Generic Manufacturers (MHRA Approved)

Product of United Kingdom

Dispensed by a licensed pharmacy in the United Kingdom

Prescription Required

Irbesartan 300mg
Irbesartan 300mg

Generic Equivalent of Avapro 300mg

Manufactured by Various UK Generic Manufacturers (MHRA Approved)

Product of United Kingdom

Dispensed by a licensed pharmacy in the United Kingdom

Prescription Required

More Generic Choices

What Avapro is and what it is used for

Aprovel belongs to a group of medicines known as angiotensin-II receptor antagonists. Angiotensin-II is a substance produced in the body which binds to receptors in blood vessels causing them to tighten. This results in an increase in blood pressure. Aprovel prevents the binding of angiotensin-II to these receptors, causing the blood vessels to relax and the blood pressure to lower. Aprovel slows the decrease of kidney function in patients with high blood pressure and type 2 diabetes. Aprovel is used in adult patients
• to treat high blood pressure (essential hypertension)
• to protect the kidney in patients with high blood pressure, type 2 diabetes and laboratory evidence of impaired kidney function.

How to take Avapro

Always take this medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure. Method of administration Aprovel is for oral use. Swallow the tablets with a sufficient amount of fluid (e.g. one glass of water). You can take Aprovel with or without food. Try to take your daily dose at about the same time each day. It is important that you continue to take Aprovel until your doctor tells you otherwise.
• Patients with high blood pressure The usual dose is 150 mg once a day. The dose may later be increased to 300 mg (two tablets a day) once daily depending on blood pressure response.
• Patients with high blood pressure and type 2 diabetes with kidney disease In patients with high blood pressure and type 2 diabetes, 300 mg (two tablets a day) once daily is the preferred maintenance dose for the treatment of associated kidney disease. The doctor may advise a lower dose, especially when starting treatment in certain patients such as those on haemodialysis, or those over the age of 75 years. The maximal blood pressure lowering effect should be reached 4-6 weeks after beginning treatment. Use in children and adolescents Aprovel should not be given to children under 18 years of age. If a child swallows some tablets, contact your doctor immediately. If you take more Aprovel than you should: If you accidentally take too many tablets, contact your doctor immediately. If you forget to take Aprovel: If you accidentally miss a daily dose, just take the next dose as normal. Do not take a double dose to make up for a forgotten dose. If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them. Some of these effects may be serious and may require medical attention. As with similar medicines, rare cases of allergic skin reactions (rash, urticaria), as well as localised swelling of the face, lips and/or tongue have been reported in patients taking irbesartan. If you get any of these symptoms or get short of breath, stop taking Aprovel and contact your doctor immediately. The frequency of the side effects listed below is defined using the following convention:

Very common: may affect more than 1 in 10 people

Common: may affect up to 1 in 10 people

Uncommon: may affect up to 1 in 100 people Side effects reported in clinical studies for patients treated with Aprovel were:


Very common (may affect more than 1 in 10 people): if you suffer from high blood pressure and type 2 diabetes with kidney disease, blood tests may show an increased level of potassium.


Common (may affect up to 1 in 10 people): dizziness, feeling sick/vomiting, fatigue and blood tests may show raised levels of an enzyme that measures the muscle and heart function (creatine kinase enzyme). In patients with high blood pressure and type 2 diabetes with kidney disease, dizziness when getting up from a lying or sitting position, low blood pressure when getting up from a lying or sitting position, pain in joints or muscles and decreased levels of a protein in the red blood cells (haemoglobin) were also reported.


Uncommon (may affect up to 1 in 100 people): heart rate increased, flushing, cough, diarrhoea, indigestion/heartburn, sexual dysfunction (problems with sexual performance), chest pain. Some undesirable effects have been reported since marketing of Aprovel. Undesirable effects where the frequency is not known are: feeling of spinning, headache, taste disturbance, ringing in the ears, muscle cramps, pain in joints and muscles, reduced number of platelets, abnormal liver function, increased blood potassium levels, impaired kidney function, inflammation of small blood vessels mainly affecting the skin (a condition known as leukocytoclastic vasculitis), and severe allergic reactions (anaphylactic shock).

Uncommon cases of jaundice (yellowing of the skin and/or whites of the eyes) have also been reported.

Reporting of side effects If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet United Kingdom You can also report side effects directly via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store. Ireland You can also report side effects directly via HPRA Pharmacovigilance, Earlsfort Terrace, IRL - Dublin 2; Tel: +353 1 6764971; Fax: +353 1 6762517. Website: www.hpra.ie; E-mail: [email protected] By reporting side effects you can help provide more information on the safety of this medicine.

How to Store Avapro

Keep this medicine out of the sight and reach of children. Do not use this medicine after the expiry date which is stated on the carton and on the blister after EXP. The expiry date refers to the last day of that month. Do not store above 30°C. Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.

Fast Shipping

2 to 3 weeks on average

The average shipping time is 2 weeks in North America and 4 weeks internationally. We offer free shipping on all orders shipped to North America. Shipping is a flat rate of $20.00 for all other countries.

Price Match Guarantee

If you have been prescribed medication by your doctor and cannot afford the high price at your local pharmacy, Medix Pharmacy is the solution for you. All orders are backed with a price match and satisfaction guarantee.

Your Trusted Pharmacy Referral Service

Medix Pharmacy is an international pharmacy referral service. With a network of licensed pharmacy partners in Canada, United Kingdom, Australia, and New Zealand, we are able to help you lower the costs of your medications.

Our pharmacy partners are all thoroughly vetted and qualified to ensure that the medication you receive is cost effective, safe and effective. Because we only work with licensed pharmacies, you can rest assured that your medication is safe, effective, and genuine.

  • Free standard delivery to your door, to any international address
  • Option to add Tracked Deliveries
  • Handy reminders to re-order so you do not run out
  • Professional & Knowledgeable Customer Services Team
  • Save time, with no need for repeated trips to your physician or local drugstore

With a dedicated customer service team, free standard shipping, and a record of providing significant saving for our customers, we believe that you do not need to compromise quality or safety in your search for value.

If you are unable to find your prescribed medicine on our website, please fill out the form below and we will confirm pricing and availability within 1 business day. You may also call us at 1-866-500-6633 and one of our patient care representatives will be happy to assist you.