Brand Name Choices
What Azilect is and what it is used for
AZILECT contains the active substance rasagiline and it is used for the treatment of Parkinson’s disease in adults. It can be used together with or without Levodopa (another medicine that is used to treat Parkinson’s disease). With Parkinson’s disease, there is a loss of cells that produce dopamine in the brain. Dopamine is a chemical in the brain involved in movement control. AZILECT helps to increase and sustain levels of dopamine in the brain.
How to take Azilect
Always take this medicine exactly as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure. REG0184732 Version 9.0 Effective Page 27 of 33 28 The recommended dose of AZILECT is 1 tablet of 1 mg taken by mouth once daily. AZILECT may be taken with or without food. If you take more AZILECT than you should If you think that you may have taken too many AZILECT tablets, contact your doctor or pharmacist immediately. Take the AZILECT carton/ blister or bottle with you to show the doctor or pharmacist. Symptoms reported following overdose of AZILECT included slightly euphoric mood (light form of mania), extremely high blood pressure and serotonin syndrome (see section 4). If you forget to take AZILECT Do not take a double dose to make up for a forgotten dose. Take the next dose normally, when it is time to take it. If you stop taking AZILECT Do not stop taking AZILECT without first talking to your doctor. If you have any further questions on the use of this medicine, ask your doctor or pharmacist.
Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.
Contact you doctor right away if you notice any of the following symptoms. You may need urgent
medical advice or treatment:
•If you develop unusual behaviours such as compulsions, obsessive thoughts, addictive gambling, excessive shopping or spending, impulsive behaviour and an abnormally high sex drive or an increase in sexual thoughts (impulse control disorders) (see section 2).
•If you see or hear things which are not there (hallucinations).
•Any combination of hallucinations, fever, restlessness, tremor and sweating (serotonin syndrome)
•If you notice any suspicious skin changes because there is a higher risk of skin cancer (not exclusively melanoma) in patients with Parkinson’s disease (see section 2).
Other side effects
Very common (may affect more than 1 in 10 people)
•Involuntary movements (dyskinesia)
Common (may affect up to 1 in 10 people)
•General feeling of being unwell (malaise)
•Chest pain (angina pectoris)
•Low blood pressure when rising to a standing position with symptoms like dizziness/lightheadedness (orthostatic hypotension)
•Nausea and vomiting REG0184732 Version 9.0 Effective Page 28 of 33 29
•Abnormal results of blood tests (leucopenia)
•Joint pain (arthralgia)
•Joint inflammation (arthritis)
•Numbness and muscle weakness of the hand (carpal tunnel syndrome)
•Difficulty in muscular coordination (balance disorder)
•Prolonged muscle contractions (dystonia)
•Runny nose (rhinitis)
•Irritation of the skin (dermatitis)
•Bloodshot eyes (conjunctivitis)
Uncommon (may affect up to 1 in 100 people)
•Stroke (cerebrovascular accident)
•Heart attack (myocardial infarction)
•Blistering rash (vesiculobullous rash)
Not known: frequency cannot be estimated from the available data
•Elevated blood pressure
•Sudden onset of sleep
Reporting of side effects If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via United Kingdom Yellow Card Scheme Website: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store Ireland HPRA Pharmacovigilance Earlsfort Terrace IRL
•Dublin 2 Tel: +353 1 6764971 Fax: +353 1 6762517 Website: www.hpra.ie e-mail: mailto:[email protected] Malta ADR Reporting Website: www.medicinesauthority.gov.mt/adrportal By reporting side effects you can help provide more information on the safety of this medicine
How to Store Azilect
Keep this medicine out of the sight and reach of children. REG0184732 Version 9.0 Effective Page 29 of 33 30 Do not use this medicine after the expiry date which is stated on the carton, bottle or blister after EXP. The expiry date refers to the last day of that month. Do not store above 30oC. Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.
2 to 3 weeks on average
The average shipping time is 2 weeks in North America and 4 weeks internationally. We offer free shipping on all orders shipped to North America. Shipping is a flat rate of $20.00 for all other countries.
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