What Imuran is and what it is used for
Imuran injection contains a medicine called azathioprine. This belongs to a group of
medicines called immunosuppressants. These medicines reduce the activity of your body's
Imuran is used to:
• stop your body rejecting an organ transplant
• treat diseases where your immune system reacts against your own body (called autoimmune diseases, such as rheumatoid arthritis). Ask your doctor, nurse or pharmacist if you would like any further explanation about these uses.
How to take Imuran
The dose of Imuran you have depends on your illness and how bad it is. The dose also
depends on your age, your weight and how well your liver and kidneys are working. Your
doctor will explain this to you.
To stop your body rejecting an organ transplant
On the first day
• the usual dose is up to 5 mg per kg of body weight. For the rest of your treatment
• you will have between 1 and 4 mg per kg of body weight each day. For other conditions At the start of your treatment
• you will have 1 to 3 mg per kg of body weight each day
• your doctor may reduce your dose later.If you have more Imuran than you should Your doctor will give you Imuran so it is unlikely that you will receive too much. If you think you have been given too much or have missed a dose, tell your doctor or nurse.
Possible side effects
Like all medicines, Imuran can cause side effects, although not everybody gets them.
The following side effects may happen with this medicine: If you notice any of the following serious side effects, talk to your specialist doctor or go to hospital straight away:
• allergic reaction, the signs may include:
•general tiredness, dizziness, feeling sick (nausea), being sick (vomiting) or diarrhoea
•high temperature (fever), shivering or chills
•redness of the skin or a skin rash
•pain in the muscles or joints
•changes in the amount and colour of the urine (kidney problems)
•dizziness, confusion, feeling light headed or weak, caused by low blood pressure
• you bruise more easily or notice any unusual bleeding
• you have a high temperature (fever) or other signs of an infection
• you feel extremely tired
• you notice lumps anywhere on your body
• you notice any changes to your skin, for example blisters or peeling
• your health suddenly gets worse
• you come into contact with anyone who is suffering from chickenpox or shingles. If you notice any of the above, stop having Imuran and see a doctor straight away.
Other side effects include:
Very common (affects more than 1 in 10 people)
• infections caused by a virus, fungus or bacteria
• reduction in your bone marrow function, which may make you feel unwell or show up in your blood tests
• low white blood cell level in your blood tests, which may cause an infection.
Common (affects less than 1 in 10 people)
• low blood platelet level, which may cause you to bruise or bleed easily.
Uncommon (affects less than 1 in 100 people)
• low red blood cell level, which may cause you to be tired, get headaches, be short of breath when exercising, feel dizzy and look pale
• inflammation of the pancreas, which may cause you severe upper stomach pain, with feeling sick (nausea) and being sick (vomiting)
• liver problems, which may cause pale stools, dark urine, itchiness and yellowing of your skin and eyes.
Rare (affects less than 1 in 1,000 people)
• problems with your blood and bone marrow which may cause weakness, tiredness, paleness, headaches, sore tongue, breathlessness, bruising or infectionsproblems with your bowel leading to diarrhoea, abdominal pain, constipation, feeling sick (nausea) and being sick (vomiting)
• hair loss which may get better even though you continue to take Imuran
• severe liver damage which can be life-threatening
• various types of cancers including blood, lymph and skin cancers
• sensitivity to sunlight which can cause skin discolouration or a rash.
Very rare (affects less than 1 in 10,000 people)
• inflammation of your lungs causing breathlessness, cough and a fever. If any of the side effects gets serious, or if you notice any other side effects not listed in this leaflet, please tell your doctor, nurse or pharmacist
How to Store Imuran
Do not store above 25°C.
• Protect from light and keep dry.
• Keep out of the reach and sight of children.
• Do not use Imuran after the expiry date which is stated on the label. The expiry date refers to the last day of that month.
• Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.
2 to 3 weeks on average
The average shipping time is 2 weeks in North America and 4 weeks internationally. We offer free shipping on all orders shipped to North America. Shipping is a flat rate of $20.00 for all other countries.
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