COVID-19 SERVICE UPDATE – JULY 2021
Shipping Update

We are now seeing improvements in our shipping times. However, things are not yet back to normal and there are still some delays occurring. We will provide updates as the situation changes.

Our normal shipping time averages 1 - 2 weeks. Due to the pandemic, shipments may sometimes take an additional 2 – 4 weeks to arrive, depending on the source country of your order. Shipments from the United Kingdom and Canada are generally quicker than from other countries.

Please note that these times are averages and individual shipping times will vary. We highly recommend that you place your order at least 2 – 4 weeks or more ahead of your normal reorder time to avoid running out of your medication.

We offer a shipping guarantee when you place an order with us. If your order does not arrive within 6 weeks from the date it was shipped, we will re-ship your order to you at no additional cost.

Call Center

Our call center hours of operation are 6:00 am – 9:00 pm Central Time on Monday to Friday, and 7:00 am – 7:00 pm Central Time on Saturday and Sunday.

If you are experiencing increased hold times or are calling outside of these hours, please leave us a message or send us an email and we will get back to you as soon as we can. Due to increased demand on telephone networks worldwide, you may experience some intermittent connection problems. If this happens our agents will call you back.

Our Commitment

If you have any questions about any changes in our service please do not hesitate to contact us. Our staff are working tirelessly to ensure the timely fulfillment and delivery of all orders. The health and safety of our customers and staff is our highest priority and we remain committed to providing service at the highest level.

We appreciate your business and thank you for your continued support.


Management and Staff
Medix Pharmacy

Jentadueto
(Linagliptin/Metformin Hydrochloride)

Prescription Settings Edit

Brand Name Choices

Jentadueto 2.5/500mg
Jentadueto 2.5/500mg

Linagliptin/Metformin Hydrochloride

Manufactured by Boehringer Ingelheim

Product of Canada

Dispensed by an approved Canadian pharmacy partner

Prescription Required

Jentadueto 2.5/1000mg
Jentadueto 2.5/1000mg

Linagliptin/Metformin Hydrochloride

Manufactured by Boehringer Ingelheim

Product of United Kingdom

Dispensed by a licensed pharmacy in the United Kingdom

Prescription Required

Parallel Import

Generic Choices

No generic medication is available for Jentadueto (Linagliptin/Metformin Hydrochloride)

What Jentadueto is and what it is used for

The name of your tablet is Jentadueto. It contains two different active substances linagliptin and metformin.
•Linagliptin belongs to a class of medicines called DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors).
•Metformin belongs to a class of medicines called biguanides. How Jentadueto works The two active substances work together to control blood sugar levels in adult patients with a form of diabetes called ‘type 2 diabetes mellitus’. Along with diet and exercise, this medicine helps to improve the levels and effects of insulin after a meal and lowers the amount of sugar made by your body. This medicine can be used alone or with certain other medicines for diabetes like sulphonylureas, empagliflozin, or insulin.

How to take Jentadueto

Always take this medicine exactly as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure. How much to take The amount of Jentadueto that you will take varies depending on your condition and the doses you currently take of metformin and/or individual tablets of linagliptin and metformin. Your doctor will tell you exactly the dose of this medicine to take. How to take this medicine
•one tablet twice daily by mouth in the dose prescribed by your doctor.
•with meals to lower your chance of an upset stomach. You should not exceed the maximum recommended daily dose of 5 mg linagliptin and 2,000 mg metformin hydrochloride. Continue to take Jentadueto as long as your doctor prescribes it so you can continue to help control your blood sugar. Your doctor may prescribe this medicine together with another oral anti-diabetic medicine or insulin. Remember to take all medicines as directed by your doctor to achieve the best results for your health. You should continue your diet during treatment with Jentadueto and take care that your carbohydrate intake is equally distributed over the day. If you are overweight, continue your energy-restricted diet as instructed. This medicine alone is unlikely to cause abnormally low blood sugar (hypoglycaemia). When Jentadueto is used with a sulphonylurea medicine or with insulin, low blood sugar can occur and your doctor may reduce the dose of your sulphonylurea or insulin. If you take more Jentadueto than you should If you take more Jentadueto tablets than you should have, you may experience lactic acidosis. Symptoms of lactic acidosis are non-specific such as feeling or being very sick, vomiting, stomach ache with muscle cramps, a general feeling of not being well with severe tiredness, and difficulty in breathing. Further symptoms are reduced body temperature and heartbeat. If this happens to you, you may need immediate hospital treatment, as lactic acidosis can lead to coma. Stop taking this medicine immediately and contact a doctor or the nearest hospital straight away (see section 2). Take the medicine pack with you. If you forget to take Jentadueto If you forget to take a dose, take it as soon as you remember it. However, if it is nearly time for the next dose, skip the missed dose. Do not take a double dose to make up for a forgotten dose. Never take two doses at the same time (morning or evening). If you stop taking Jentadueto Keep taking Jentadueto until your doctor tells you to stop. This is to help keep your blood sugar under control. 5 If you have any further questions on the use of this medicine, ask your doctor, pharmacist or nurse

Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them. Some symptoms need immediate medical attention You should stop taking Jentadueto and see your doctor straight away if you experience the following symptoms of low blood sugar (hypoglycaemia): trembling, sweating, anxiety, blurred vision, tingling lips, paleness, mood change, or confusion. Hypoglycaemia (frequency very common (may affect more than 1 in 10 people)) is an identified side effect for the combination of Jentadueto plus sulphonylurea and for the combination Jentadueto plus insulin. Jentadueto may cause a very rare (may affect up to 1 user in 10,000), but very serious side effect called lactic acidosis (see section ‘Warnings and precautions’). If this happens you must stop taking Jentadueto and contact a doctor or the nearest hospital immediately, as lactic acidosis may lead to coma. Some patients have experienced inflammation of the pancreas (pancreatitis; frequency not known, frequency cannot be estimated from the available data). STOP taking Jentadueto and contact a doctor immediately if you notice any of the following serious side effects:
•Severe and persistent pain in the abdomen (stomach area) which might reach through to your back, as well as nausea and vomiting, as it could be a sign of an inflamed pancreas (pancreatitis).

Other side effects of Jentadueto include: Some patients have experienced allergic reactions (frequency rare (may affect up to 1 in 1,000 people)), which may be serious, including wheezing and shortness of breath (bronchial hyperreactivity; frequency uncommon (may affect up to 1 in 100 people)). Some patients experienced rash (frequency uncommon), hives (urticaria; frequency rare), and swelling of the face, lips, tongue, and throat that may cause difficulty in breathing or swallowing (angioedema; frequency rare). If you experience any of the signs of illness mentioned above, stop taking Jentadueto and call your doctor right away. Your doctor may prescribe a medicine to treat your allergic reaction and a different medicine for your diabetes. Some patients have had the following side effects while taking Jentadueto:


Common (may affect up to 1 in 10 people): diarrhoea, blood enzyme increase (lipase increase)


Uncommon: inflamed nose or throat (nasopharyngitis), cough, loss of appetite (decreased appetite), feeling sick (nausea) or being sick (vomiting), blood enzyme increase (amylase increase), itching (pruritus)
•Frequency not known: blistering of skin (bullous pemphigoid) Side effects when taking linagliptin alone: All side effects of linagliptin alone are listed for Jentadueto. Some patients have experienced the following side effects while taking Jentadueto with insulin


Uncommon: liver function disorders, constipation Please refer to the Package Leaflet for insulin for additional information. Side effects when taking metformin alone, that were not described for Jentadueto:


Very common: abdominal pain.


Common (may affect up to 1 in 10 people): a metallic taste (taste disturbance).


Very rare (may affect up to 1 in 10,000 people): decreased vitamin B12 levels, hepatitis (a problem with your liver), skin reaction as redness of the skin (erythema, rash) and urticaria. 6

Reporting of side effects If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly (see details below). By reporting side effects you can help provide more information on the safety of this medicine. Ireland HPRA Pharmacovigilance Earlsfort Terrace IRL
•Dublin 2 Tel: +353 1 6764971 Fax: +353 1 6762517 Website: www.hpra.ie e-mail: [email protected] Malta ADR Reporting Website: www.medicinesauthority.gov.mt/adrportal United Kingdom Yellow Card Scheme Website: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store

How to Store Jentadueto

Keep this medicine out of the sight and reach of children. Do not use this medicine after the expiry date which is stated on the blister, bottle and carton after EXP. The expiry date refers to the last day of that month. This medicine does not require any special temperature storage conditions. Blister: Store in the original package in order to protect from moisture. Bottle: Keep the bottle tightly closed in order to protect from moisture. Do not use this medicine if the package is damaged or shows signs of tampering. Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.

Fast Shipping

2 to 3 weeks on average

The average shipping time is 2 weeks in North America and 4 weeks internationally. We offer free shipping on all orders shipped to North America. Shipping is a flat rate of $20.00 for all other countries.

Price Match Guarantee

If you have been prescribed medication by your doctor and cannot afford the high price at your local pharmacy, Medix Pharmacy is the solution for you. All orders are backed with a price match and satisfaction guarantee.

Your Trusted Pharmacy Referral Service

Medix Pharmacy is an international pharmacy referral service. With a network of licensed pharmacy partners in Canada, United Kingdom, Australia, and New Zealand, we are able to help you lower the costs of your medications.

Our pharmacy partners are all thoroughly vetted and qualified to ensure that the medication you receive is cost effective, safe and effective. Because we only work with licensed pharmacies, you can rest assured that your medication is safe, effective, and genuine.

  • Free standard delivery to your door, to any international address
  • Option to add Tracked Deliveries
  • Handy reminders to re-order so you do not run out
  • Professional & Knowledgeable Customer Services Team
  • Save time, with no need for repeated trips to your physician or local drugstore

With a dedicated customer service team, free standard shipping, and a record of providing significant saving for our customers, we believe that you do not need to compromise quality or safety in your search for value.

If you are unable to find your prescribed medicine on our website, please fill out the form below and we will confirm pricing and availability within 1 business day. You may also call us at 1-866-500-6633 and one of our patient care representatives will be happy to assist you.