What Namenda is and what it is used for
Alzhok belongs to a group of medicines known as anti-dementia medicines. Memory loss in Alzheimer’s disease is due to a disturbance of message signals in the brain. The brain contains socalled N-methyl-D-aspartate (NMDA)-receptors that are involved in transmitting nerve signals important in learning and memory. Alzhok belong to a group of medicines called NMDA-receptor antagonists. Alzhok act on these NMDAreceptors improving the transmission of nerve signals and the memory. Alzhok is used for the treatment of patients with moderate to severe Alzheimer’s disease in adults.
How to take Namenda
Always take this medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you are not
The recommended treatment dose of 20 mg per day is achieved by a gradual increase of Alzhok dose during the first 3
weeks of treatment. The treatment scheme is also indicated on the treatment initiation pack. Take one tablet once a
week 1 One 5 mg tablet
week 2 One 10 mg tablet
week 3 One 15 mg tablet
week 4 and beyond One 20 mg tablet
The usual starting dose is one 5 mg tablet once a day for the first week. This is increased to one 10 mg tablet once a
day in the second week and to one 15 mg tablet once a day in the third week. From the fourth week on, the usual dose
is 20 mg once a day (two tablets of 10 mg or 1 tablet of 20 mg).
Dosage in patients with impaired kidney function
If you have impaired (poor) kidney function, your doctor will decide upon a dose that suits your condition. In this
case, monitoring of your kidney function should be performed by your doctor at specified intervals.
Method of administration
• This medicine should be administered orally (by mouth) once a day.
• To benefit from your medicine you should take it regularly every day at the same time of the day.
• The tablets can be taken with or without food.
• The tablets are best taken dissolved in half a glass of water, however, they can also be taken whole, with a drink of water.
• Dissolve the tablet, that your doctor has told you to take, in a glass of water, and then drink all of it immediately.
• Do not leave your drink where someone else may drink it as your medicine could harm them. Duration of treatment Continue to take this medicine as long as it is of benefit to you. Your doctor should assess your treatment on a regular basis. If you take more Alzhok than you should
•In general, taking more Alzhok than you have been prescribed should not result in any harm to you. You may experience increased symptoms as described in section 4 “Possible side effects”.
•If you take a large overdose of Alzhok, contact your doctor or get medical advice, as you may need medical attention. If you forget to take Alzhok
•If you find you have forgotten to take your dose of Alzhok, wait and take your next dose at the usual time.
•Do not take a double dose to make up for a forgotten dose. If you have any further questions on the use of this medicine, ask your doctor or pharmacist
Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.
In general, the observed side effects are mild to moderate.
Alzheimer’s disease has been associated with depression, suicidal thoughts and suicide. These problems have been
experienced by patients being treated with Alzhok.
Common (may affect up to 1 in 10 people):
• Elevated liver function test results.
• Dizziness, problems with your balance.
• Shortness of breath.
• High blood pressure.
• Drug hypersensitivity.
Uncommon (may affect up to 1 in 100 people):
• Fungal infections.
• Being sick (vomiting).
• Abnormal gait.
• Heart failure.
• Blood clots in your veins (thrombosis/thromboembolism). Very
Rare (may affect up to 1 in 10,000 people):
Not known (frequency cannot be estimated from the available data):
• Inflammation of the pancreas.
• Inflammation of the liver (hepatitis).
• Psychotic reactions.
Reporting of side effects If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the national reporting system. By reporting side effects you can help provide more information on the safety of this medicine. United Kingdom Yellow Card Scheme Website: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store Malta ADR Reporting Website: www.medicinesauthority.gov.mt/adrportal
How to Store Namenda
Keep this medicine out of the sight and reach of children. Do not use this medicine after the expiry date which is stated on the carton and the blister after EXP. The expiry date refers to the last day of that month. This medicinal product does not require any special temperature storage conditions. Store in the original package in order to protect from moisture. Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environmen
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