Sprycel

Before taking dasatinib, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Sprycel may contain inactive ingredients (such as lactose), which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using Sprycel, tell your doctor or pharmacist your medical history,bleeding problems, current/recent infection, heart problems (such as irregular heartbeat), liver problems (such as hepatitis B). Dasatinib may cause a condition that affects the heart rhythm (QT prolongation). QT prolongation can rarely cause serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that need medical attention right away. The risk of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that may cause QT prolongation. Before using dasatinib,certain heart problems (heart failure, slow heartbeat, QT prolongation in the EKG), family history of certain heart problems (QT prolongation in the EKG, sudden cardiac death). Low levels of potassium or magnesium in the blood may also increase your risk of QT prolongation. This risk may increase if you use certain drugs (such as diuretics/"water pills") or if you have conditions such as severe sweating, diarrhea, or vomiting. Talk to your doctor about using dasatinib safely. Dasatinib can make you more likely to get infections or may worsen any current infections. Avoid contact with people who have infections that may spread to others (such as chickenpox, measles, flu). Consult your doctor if you have been exposed to an infection or for more details. Tell your health care professional that you are using dasatinib before having any immunizations/vaccinations. Avoid contact with people who have recently received live vaccines (such as flu vaccine inhaled through the nose). To lower the chance of getting cut, bruised, or injured, use caution with sharp objects like razors and nail cutters, and avoid activities such as contact sports. Sprycel may affect a child's bone growth and development. Consult the doctor or pharmacist for more details. Older adults may be more sensitive to the side effects of Sprycel, especially diarrhea, swelling hands/ankles/feet, sudden/unexplained weight gain, unusual tiredness, shortness of breath, and QT prolongation (see above). Since Sprycel can be absorbed through the skin and lungs and may harm an unborn baby, women who are pregnant or who may become pregnant should not handle Sprycel or breathe the dust from the tablets. Tell your doctor if you are pregnant or plan to become pregnant. Your doctor may order a pregnancy test before starting Sprycel. You should not become pregnant while using dasatinib. Dasatinib may harm an unborn baby. Women of childbearing age should ask about reliable forms of birth control while using Sprycel and for 30 days after the last dose. Men with female partners of childbearing age should use reliable forms of birth control while using Sprycel and for 30 days after the last dose. If you or your partner becomes pregnant, talk to your doctor right away about the risks and benefits of Sprycel. It is unknown if Sprycel passes into breast milk. Because of the possible risk to the infant, breast-feeding while using Sprycel and for 2 weeks after stopping treatment is not recommended. Consult your doctor before breast-feeding.