COVID-19 SERVICE UPDATE – JULY 2021
Shipping Update

We are now seeing improvements in our shipping times. However, things are not yet back to normal and there are still some delays occurring. We will provide updates as the situation changes.

Our normal shipping time averages 1 - 2 weeks. Due to the pandemic, shipments may sometimes take an additional 2 – 4 weeks to arrive, depending on the source country of your order. Shipments from the United Kingdom and Canada are generally quicker than from other countries.

Please note that these times are averages and individual shipping times will vary. We highly recommend that you place your order at least 2 – 4 weeks or more ahead of your normal reorder time to avoid running out of your medication.

We offer a shipping guarantee when you place an order with us. If your order does not arrive within 6 weeks from the date it was shipped, we will re-ship your order to you at no additional cost.

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Our call center hours of operation are 6:00 am – 9:00 pm Central Time on Monday to Friday, and 7:00 am – 7:00 pm Central Time on Saturday and Sunday.

If you are experiencing increased hold times or are calling outside of these hours, please leave us a message or send us an email and we will get back to you as soon as we can. Due to increased demand on telephone networks worldwide, you may experience some intermittent connection problems. If this happens our agents will call you back.

Our Commitment

If you have any questions about any changes in our service please do not hesitate to contact us. Our staff are working tirelessly to ensure the timely fulfillment and delivery of all orders. The health and safety of our customers and staff is our highest priority and we remain committed to providing service at the highest level.

We appreciate your business and thank you for your continued support.


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Medix Pharmacy

Taclonex Suspension
(Betamethasone Dipropionate/Calcipotriol)

Prescription Settings Edit

Brand Name Choices

Taclonex 0.064%/0.005%
Taclonex 0.064%/0.005% Gel

Marketed as Dovobet Gel 0.05%/0.005% in United Kingdom

Betamethasone Dipropionate/Calcipotriol

Manufactured by Leo Pharma Ltd

Product of United Kingdom

Dispensed by a licensed pharmacy in the United Kingdom

Prescription Required

Parallel Import

Taclonex 0.064%/0.005%
Taclonex 0.064%/0.005% Gel

Marketed as Dovobet Gel 0.05%/0.005% in Canada

Betamethasone Dipropionate/Calcipotriol

Manufactured by LEO Pharma Inc.

Product of Canada

Dispensed by an approved Canadian pharmacy partner

Prescription Required

More Brand Name Choices

Generic Choices

No generic medication is available for Taclonex Suspension (Betamethasone Dipropionate/Calcipotriol)

What Taclonex Suspension is and what it is used for

Dovobet is used as topical treatment of scalp psoriasis in adults and on the skin of other body areas to treat mild to moderate plaque psoriasis (psoriasis vulgaris) in adults. Psoriasis is caused by your skin cells being produced too quickly. This causes redness, scaling and thickness of your skin. Dovobet contains calcipotriol and betamethasone. Calcipotriol helps to bring the rate of skin cell growth back to normal and betamethasone acts to reduce inflammation

How to take Taclonex Suspension

Always use this medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure. How to put on Dovobet: Cutaneous use. Instructions for proper use
• Use only on your psoriasis and do not use on skin which does not have psoriasis
• Shake the bottle before use and remove the cap
• Squeeze the gel onto a clean finger or directly onto the area affected by psoriasis
• Apply Dovobet to the affected area with your fingertips, and rub it in gently until the area affected by psoriasis is covered by a thin layer of gel
• Do not bandage, tightly cover or wrap the treated skin area
• Wash your hands well after using Dovobet. This will avoid accidentally spreading the gel to other parts of your body (especially the face, mouth and eyes)
• Do not worry if some gel accidentally gets on normal skin near your psoriasis, but wipe it off if it spreads too far
• In order to achieve optimal effect, it is recommended not to take a shower or bath immediately after application of Dovobet gel
• After applying the gel, avoid contact with textiles which are easily stained by grease (e.g. silk).

Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them. Serious side effects Tell your doctor/nurse immediately or as soon as possible if any of the following happens. You may have to stop your treatment. The following serious side effects have been reported for Dovobet:

Uncommon (may affect up to 1 in 100 people):
• Worsening of your psoriasis. If your psoriasis gets worse, tell your doctor as soon as possible. Some serious side effects are known to be caused by betamethasone (a strong steroid), one of the ingredients in Dovobet. You should tell your doctor as soon as possible if any of the serious side effects occur. These side effects are more likely to happen after long-term use, use in skin folds (e.g. groin, armpits or under breasts), use under occlusion, or use on large areas of skin. The side effects include the following:
• Your adrenal glands may stop working properly. Signs are tiredness, depression and anxiety
• Cataracts (signs are cloudy and foggy vision, difficulty seeing at night and sensitivity to light) or an increase in pressure inside the eye (signs are eye pain, red eye, decreased or cloudy vision) What is in this leaflet 1. What Dovobet® is and what it is used for 2. What you need to know before you use Dovobet® 3. How to use Dovobet® 4. Possible side effects 5. How to store Dovobet® 6. Contents of the pack and other information 1. WHAT DOVOBET® IS AND WHAT IT IS USED FOR Dovobet is used as topical treatment of scalp psoriasis in adults and on the skin of other body areas to treat mild to moderate plaque psoriasis (psoriasis vulgaris) in adults. Psoriasis is caused by your skin cells being produced too quickly. This causes redness, scaling and thickness of your skin. Dovobet contains calcipotriol and betamethasone. Calcipotriol helps to bring the rate of skin cell growth back to normal and betamethasone acts to reduce inflammation. 2. WHAT YOU NEED TO KNOW BEFORE YOU USE DOVOBET® Do not use Dovobet:
• if you are allergic (hypersensitive) to calcipotriol, betamethasone or any of the other ingredients of this medicine (listed in section 6)
• if you have problems with calcium levels in your body (ask your doctor)
• if you have certain types of psoriasis: these are erythrodermic, exfoliative and pustular (ask your doctor). As Dovobet contains a strong steroid, do NOT use it on skin affected by:
• skin infections caused by viruses (e.g. cold sores or chicken pox)
• skin infections caused by a fungus (e.g. athlete’s foot or ringworm)
• skin infections caused by bacteria
• skin infections caused by parasites (e.g. scabies)
• tuberculosis (TB)
• perioral dermatitis (red rash around the mouth)
• thin skin, easily damaged veins, stretch marks
• ichthyosis (dry skin with fish-like scales)
• acne (pimples)
• rosacea (severe flushing or redness of the skin on the face)
• ulcers or broken skin. Warnings and precautions Talk to your doctor/nurse/pharmacist before and during use of Dovobet if:
• you are using other medicines that contain corticosteroids as you may get side effects
• you have used this medicine for a long time and plan to stop (as there is a risk your psoriasis will get worse or ‘flare up’ when steroids are stopped suddenly)
• you have diabetes mellitus (diabetes) as your blood sugar/glucose level may be affected by the steroid
• your skin becomes infected as you may need to stop your treatment
• you have a certain type of psoriasis called guttate psoriasis
• you experience blurred vision or other visual disturbances. Special precautions
• Avoid use on more than 30% of your body or using more than 15 grams per day
• Avoid using under a bathing cap, bandages or dressings as it increases the absorption of the steroid
• Avoid use on large areas of damaged skin, on mucous membranes, or in skin folds (groin, armpits, under breasts) as it increases the absorption of the steroid
• Avoid use on your face or genitals (sex organs) as they are very sensitive to steroids
• Avoid excessive sunbathing, excessive use of solarium and other forms of light treatment. Children Dovobet is not recommended for the use in children below the age of 18 years. Other medicines and Dovobet Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines. Pregnancy and breast-feeding If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor for advice before using this medicine. If your doctor has agreed that you can breast-feed, take care and do not apply Dovobet to the breast area. Driving and using machines This medicine should not have any effect on your ability to drive or use machines. Dovobet contains butylated hydroxytoluene (E321) Dovobet contains butylated hydroxytoluene (E321), which may cause local skin reactions (e.g. contact dermatitis), or irritation to the eyes and mucous membranes. 3. HOW TO USE DOVOBET® Always use this medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure. How to put on Dovobet: Cutaneous use. Instructions for proper use
• Use only on your psoriasis and do not use on skin which does not have psoriasis
• Shake the bottle before use and remove the cap
• Squeeze the gel onto a clean finger or directly onto the area affected by psoriasis
• Apply Dovobet to the affected area with your fingertips, and rub it in gently until the area affected by psoriasis is covered by a thin layer of gel
• Do not bandage, tightly cover or wrap the treated skin area
• Wash your hands well after using Dovobet. This will avoid accidentally spreading the gel to other parts of your body (especially the face, mouth and eyes)
• Do not worry if some gel accidentally gets on normal skin near your psoriasis, but wipe it off if it spreads too far
• In order to achieve optimal effect, it is recommended not to take a shower or bath immediately after application of Dovobet gel
• After applying the gel, avoid contact with textiles which are easily stained by grease (e.g. silk). If you have scalp psoriasis
• Before applying Dovobet to the scalp, comb the hair to remove any loose scales. Tilt your head to make sure Dovobet does not run Package leaflet: Information for the user Dovobet® 50 micrograms/g + 0.5 mg/g gel calcipotriol/betamethasone Read all of this leaflet carefully before you start using this medicine because it contains important information for you.
• Keep this leaflet. You may need to read it again.
• If you have any further questions, ask your doctor, pharmacist or nurse.
• This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.
• If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. See section 4. 059840 059840 Dovobet® Gel 1 Shake bottle before use. Dovobet® Gel 2 Apply a drop of Dovobet to fingertip. Apply directly to scalp areas where you can feel the raised plaque and rub the Dovobet gel on to the skin. Depending on the affected area 1-4 g (up to 1 teaspoon) is normally enough. 3 5 6 Leave the shampoo on the scalp for a couple of minutes before washing. Wash your hair as usual. 4 Apply a mild shampoo to the dry hair, especially to those areas where the gel was applied. In order to achieve optimal effect, it is recommended that the hair is not washed immediately after application of Dovobet. Let Dovobet remain on the scalp during the night or during the day. When washing hair after application the following instructions might be useful: If necessary, repeat steps 4-6 once or twice. Ireland Scale Get-up Matrial No Sent by e-mail Subject Date Colour Sign. Date Sign. Preparation Place of production Strength Packsize Comments: ▲ 100% GB+IE 059840 INS 160 x 600 mm 10/01/18 Black OMA Dovobet® gel Font size: 9 pt SOP_000647, SOP_000962, SOP_003993 and SOP_008676 SOP_000647, SOP_000962 and SOP_008676 SOP_000647, SOP_000962 and SOP_008676 9. EBD 12/10/18 600 mm 160 mm Page 2 300 mm INS015-01
• Infections (because your immune system, which fights infections, may be suppressed or weakened)
• Pustular psoriasis (a red area with yellowish pustules usually on the hands or feet). If you notice this, stop using Dovobet and tell your doctor as soon as possible
• Impact on the metabolic control of diabetes mellitus (if you have diabetes you may experience fluctuations in the blood glucose levels). Serious side effects known to be caused by calcipotriol:
• Allergic reactions with deep swelling of the face or other parts of the body such as the hands or feet. Swelling of the mouth/throat and trouble breathing may occur. If you have an allergic reaction, stop using Dovobet, tell your doctor immediately or go to the casualty department at your nearest hospital
• Treatment with this gel may cause the level of calcium in your blood or urine to increase (usually when too much gel has been used). Signs of increased calcium in blood are excessive secretion of urine, constipation, muscle weakness, confusion and coma. This can be serious, and you should contact your doctor immediately. However, when the treatment is stopped, the levels return to normal. Less serious side effects The following less serious side effects have been reported for Dovobet.

Common side effects (may affect up to 1 in 10 people):
• Itching.

Uncommon (may affect up to 1 in 100 people):
• Eye irritation
• Burning sensation of the skin
• Skin pain or irritation
• Inflammation or swelling of the hair root (folliculitis)
• Rash with inflammation of the skin (dermatitis)
• Redness of the skin due to widening of the small blood vessels (erythema)
• Acne (pimples)
• Dry skin
• Rash
• Pustular rash
• Infection of the skin.

Rare (may affect up to 1 in 1,000 people):
• Allergic reactions
• Stretch marks
• Skin exfoliation
• Rebound effect: A worsening of symptoms/psoriasis after ended treatment. Frequency not known (frequency cannot be estimated from the available data):
• White or grey hair can transiently change to a yellowish colour at the application site when used on the scalp
• Blurred vision. Less serious side effects caused by using betamethasone, especially for a long time, include the following. You should tell your doctor or nurse as soon as possible if you notice any of them:
• Thinning of the skin
• Appearance of surface veins or stretch marks
• Changes in hair growth
• Red rash around the mouth (perioral dermatitis)
• Skin rash with inflammation or swelling (allergic contact dermatitis)
• Golden coloured gel-filled bumps (colloid milia)
• Lightening of skin colour (depigmentation)
• Inflammation or swelling of the hair root (folliculitis). Less serious side effects known to be caused by calcipotriol include the following:
• Dry skin
• Sensitivity of the skin to light resulting in a rash
• Eczema
• Itching
• Skin irritation
• Burning and stinging sensation
• Redness of the skin due to widening of the small blood vessels (erythema)
• Rash
• Rash with inflammation of the skin (dermatitis)
• Worsening of psoriasis.

Reporting of side effects If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the national reporting system. For Ireland, via HPRA Pharmacovigilance, Earlsfort Terrace, IRL
•Dublin 2; Tel: +353 1 6764971; Fax: +353 1 6762517. Website: www.hpra.ie; E-mail: [email protected] For the United Kingdom, via the Yellow Card Scheme, Website: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store. By reporting side effects you can help provide more information on the safety of this medicine

How to Store Taclonex Suspension

Keep this medicine out of the sight and reach of children
• Do not use this medicine after the expiry date, which is stated on the bottle after EXP. The expiry date refers to the last day of that month
• Do not refrigerate. Keep the bottle in the outer carton in order to protect from light
• Discard the bottle with any remaining gel 6 months after first opening. Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.

Fast Shipping

2 to 3 weeks on average

The average shipping time is 2 weeks in North America and 4 weeks internationally. We offer free shipping on all orders shipped to North America. Shipping is a flat rate of $20.00 for all other countries.

Price Match Guarantee

If you have been prescribed medication by your doctor and cannot afford the high price at your local pharmacy, Medix Pharmacy is the solution for you. All orders are backed with a price match and satisfaction guarantee.

Your Trusted Pharmacy Referral Service

Medix Pharmacy is an international pharmacy referral service. With a network of licensed pharmacy partners in Canada, United Kingdom, Australia, and New Zealand, we are able to help you lower the costs of your medications.

Our pharmacy partners are all thoroughly vetted and qualified to ensure that the medication you receive is cost effective, safe and effective. Because we only work with licensed pharmacies, you can rest assured that your medication is safe, effective, and genuine.

  • Free standard delivery to your door, to any international address
  • Option to add Tracked Deliveries
  • Handy reminders to re-order so you do not run out
  • Professional & Knowledgeable Customer Services Team
  • Save time, with no need for repeated trips to your physician or local drugstore

With a dedicated customer service team, free standard shipping, and a record of providing significant saving for our customers, we believe that you do not need to compromise quality or safety in your search for value.

If you are unable to find your prescribed medicine on our website, please fill out the form below and we will confirm pricing and availability within 1 business day. You may also call us at 1-866-500-6633 and one of our patient care representatives will be happy to assist you.